C: Use with warning if Advantages outweigh pitfalls. Animal studies demonstrate hazard and human scientific studies not obtainable or neither animal nor human scientific tests carried out. pentobarbital will lessen the extent or result of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib can be a sensitive CYP3A4 substrate. https://dog-pentobarbital06802.answerblogs.com/34795075/indicators-on-euthanasia-sodium-pentobarbital-you-should-know